Jing (Jane) Liu

Jing (Jane) Liu

Research Scientist | Bioinformatics

👋 Hi there, I’m Jing!

I’m a Bioinformatics Research Scientist at the IEH Laboratories and Consulting Group in Seattle, Washington. I earned my Ph.D. from Oklahoma State University, where I specialized in integrating wet-lab and bioinformatics approaches to develop microbiome-based alternatives to antibiotics. My current research integrates next-generation sequencing (NGS) and computational biology to address two critical challenges: the development of microbiome-based alternatives to antibiotics in poultry production, and the rapid detection of foodborne pathogens to enhance food safety.

Profile of Qualifications

  • Programming: Python, R, SQL, Perl, Linux, Bash
  • Quantitative Bioinformatics Skills: 16S rRNA gene sequencing, metagenomics, metatranscriptomics, metabolomics, bulk-RNA sequencing, single cell RNA sequencing (scRNA-seq), whole genome sequencing (WGS),CRISPR-Cas9 analysis, statistical computing, meta-analysis, machine learning in biomarker selection, database creation and maintenance.
  • Wet lab: DNA & RNA isolation & quantification, gel electrophoresis, primer design, next-generation sequencing library prep, RT-PCR, bacterial isolation & culture, mammalian cell culture, animal handling (mice, rat, chicken).

Research Interests

  • NGS data analysis pipeline development and refining: Developed data analysis workflows for NGS data analysis, statistical computing, and visualization.

  • Meta-analysis: Downloading publicly available datasets and performing meta-analyses related to research areas of interest.

  • Development of antibiotic alternatives through microbiome-based approaches: Conducted multiple animal trials and microbiome research to identify microbiome or microbial metabolites biomarkers that could be developed as antibiotic alternatives.
  • Development of Rapid Detection Methods to Improve Food Safety and Effective Foodborne Outbreak Analysis: Integrates genomic analysis and computational biology to uncover pathogenic mechanisms, trace contamination sources, and develop targeted control strategies within the food supply chain.

Education

  1. Oklahoma State University
    Ph.D. in Animal Science (Microbiology, Bioinformatics) (May. 2019 - Aug. 2024)
  2. Nanjing Agriculture University
    M.S. in Animal Science (Microbiology) (Sep. 2014 - Jun. 2017)
  3. Yangzhou University
    B.S. in Animal Science (Sep. 2010 - Jun. 2014)